Relationship between Dietary Salt and SBP Independent of other Dietary Factors
A recent study from the INTERMAP (International Study on Macro/Micro-nutrients and Blood Pressure) Research Group, published in Hypertension assessed whether the sodium- blood pressure (BP) relationship is modulated by other dietary factors. The INTERMAP study includes 4680 participants aged 40-59 years from Japan, China, United Kingdom and the United States. Dietary data was collected via four interview administrated 24-hour dietary recalls along with two 24-hr urine samples per participant. In this population 24-hr sodium excretion two standard deviations above the mean (118.7 mmol) was associated with 3.7 mmHg higher systolic BP (SBP). Controlling for 13 macro-nutrients, 12 vitamins, 7 minerals and 18 amino acids did not change the relationship between 24-hr urinary sodium and SBP. Authors concluded that these results reinforce the importance of reducing dietary salt to prevent and control hypertension.