The association between sodium and blood pressure is influenced by methods of evaluating the completeness of 24-h urine collections
Published in Nutrients on 11 September 2020, Abu Mohd Naser et al investigated whether different methods of evaluating the completeness of 24-h urine samples influences the association between sodium intake and health outcomes. A secondary analysis of three cohort studies from Bangladesh was conducted using cross-sectional sodium intake and blood pressure measures across several visits per participant, with a total 10,031 pooled . Methods of evaluating the completeness of 24-h urine samples were investigated, by comparing to two self-reported methods and four creatinine-based methods. The study found that the differing methods for determining completeness of 24-h urine samples influence the association between sodium intake and blood pressure. The authors conclude that it is preferable to us para-aminobenzoic acid to assess the completeness of 24-h urine samples to ensure robust evidence on sodium intake and health outcomes. To access the full text article, click here.